Pipeline
FIVE TARGETS. ONE PIPELINE. NO SHORTCUTS.
Live state of every candidate program. ADMET-passed counts come directly from the production DB. Each target has an independent Gate A / Gate B decision with transparent criteria.
Autoimmune
TYK2
Psoriasis, RA, Crohn's
데이터 무결성: ⚠️ CHEMBL2148 = JAK3 (실제로 TYK2 아님). 현재 라이브러리는 JAK/pan-JAK 데이터로 시드됨. 진짜 TYK2 = CHEMBL3553. 재구축 대기 — 선택성 CRO로 판정.
ADMET Passed
6,478
CRO
3 submitted
Stage
Gate B in progress
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Oncology + Obesity
TNIK
CRC, Obesity, IPF
ADMET Passed
33,755
CRO
On hold
Stage
Deprioritized — data-rich focus
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Oncology
CDK4
Breast cancer, Melanoma
데이터 무결성: 🔧 원천 재구축 진행(2026-07-18): 구 CHEMBL4036=CDK5 오염 확인 → seed를 진짜 CDK4(CHEMBL331) 1,252건으로 재구축 완료(config/daemon/seed). ⚠️ 단, 게시된 CDK4 라이브러리·통계는 daemon 재생성 사이클 완료 전까지 구 CDK5 기반 — 재생성 진행 중.
ADMET Passed
16,735
CRO
Awaiting
Stage
Awaiting CRO decision
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Oncology
CDK6
Breast cancer, NSCLC
ADMET Passed
9,186
CRO
Awaiting
Stage
Awaiting CRO decision
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Oncology
EGFR
NSCLC, Glioblastoma
ADMET Passed
5,497
CRO
Accumulating
Stage
Library buildup
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